Both Selank and Semax are melanocortins and have pleiotropic effects involved in brain health and function. Selank by itself has traditionally been prescribed for anxiety and depression. Selank has pronounced anxiolytic activity and acts as a stable neuropsychotropic, antidepressant, and anti-stress medication. Semax is used as a therapeutic for patients with pathologies related to brain circulation dysfunction. As a combination, Selank/Semax has applications in improving learning processes, exploratory behavior, regeneration and development, nociceptive and in ammatory processes, accelerate nerve regeneration and improve neuromuscular performance and overall neural health.